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Concept information

Preferred term

Fusion Regulatory Protein-1  

Type

  • Topical Descriptor

Entry terms

  • 4F2 Antigen
  • 4F2-antigen
  • Antigen 4F2
  • Antigen, CD98
  • Antigens, CD98
  • CD98 Antigen
  • CD98 Antigens
  • CD98 Transport Proteins
  • FRP 1 protein
  • FRP-1 protein
  • Transport Proteins, CD98

Scope note

  • A heterodimeric protein that is a cell surface antigen associated with lymphocyte activation. The initial characterization of this protein revealed one identifiable heavy chain (FUSION REGULATORY PROTEIN 1, HEAVY CHAIN) and an indeterminate smaller light chain. It is now known that a variety of light chain subunits (FUSION REGULATORY PROTEIN 1, LIGHT CHAINS) can dimerize with the heavy chain. Depending upon its light chain composition a diverse array of functions can be found for this protein. Functions include: type L amino acid transport, type y+L amino acid transport and regulation of cellular fusion.

History note

  • 2018 (1988)

In other languages

URI

http://www.yso.fi/onto/mesh/D027261

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