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... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Fatty Acids, Essential > Arachidonic Acids > Isoprostanes
... > Biological Factors > Inflammation Mediators > Autacoids > Eicosanoids > Arachidonic Acids > Isoprostanes
... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Eicosanoids > Arachidonic Acids > Isoprostanes

Preferred term

Isoprostanes  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Isoprostane

Scope note

  • A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the "naturally occurring" compounds.

History note

  • 2002

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URI

http://www.yso.fi/onto/mesh/D028421

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