Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Membrane Transport Proteins > Nucleocytoplasmic Transport Proteins > Karyopherins > beta Karyopherins
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Membrane Transport Proteins > Nucleocytoplasmic Transport Proteins > Karyopherins > beta Karyopherins
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Karyopherins > beta Karyopherins

Preferred term

beta Karyopherins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • beta Importins
  • Importin beta
  • Importin-beta
  • Importins, beta
  • Kap95 protein
  • Karyopherin beta
  • Karyopherin-beta
  • Karyopherin beta Subunit
  • Karyopherin-beta Subunit
  • nuclear protein, p92
  • p92 nuclear protein

Scope note

  • Nucleocytoplasmic transport molecules that bind to ALPHA KARYOPHERINS in the CYTOSOL and are involved in transport of molecules through the NUCLEAR PORE COMPLEX. Once inside the CELL NUCLEUS beta karyopherins interact with RAN GTP-BINDING PROTEIN and dissociate from alpha karyopherins. Beta karyopherins bound to RAN GTP-BINDING PROTEIN are then re-transported to the cytoplasm where hydrolysis of the GTP of RAN GTP-BINDING PROTEIN causes release of karyopherin beta.

History note

  • 2002; use BETA KARYOPHERINS (NM) 1995-2001; for IMPORTIN-BETA use KARYOPHERINS (NM) 1995-2001

In other languages

URI

http://www.yso.fi/onto/mesh/D028961

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 6/30/05