Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Activin Receptors
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Serine-Threonine Kinases > Activin Receptors
... > Enzymes and Coenzymes > Enzymes > Transferases > Phosphotransferases > Phosphotransferases (Alcohol Group Acceptor) > Protein Kinases > Protein Serine-Threonine Kinases > Activin Receptors
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Transforming Growth Factor beta > Activin Receptors
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, Transforming Growth Factor beta > Activin Receptors

Preferred term

Activin Receptors  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Activin Receptor
  • Activin Receptor like Kinase
  • Activin Receptor-like Kinase
  • Activin Receptor Like Kinases
  • Activin Receptor-Like Kinases
  • Kinase, Activin Receptor-like
  • Kinases, Activin Receptor-Like
  • Receptor, Activin
  • Receptor-like Kinase, Activin
  • Receptor-Like Kinases, Activin

Scope note

  • Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.

History note

  • 2002(1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D029404

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/25/01, last modified 4/21/21