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Preferred term

Aristolochic Acids  

Type

  • Topical Descriptor

Scope note

  • Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).

History note

  • 2003

In other languages

URI

http://www.yso.fi/onto/mesh/D034341

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