Concept information
Preferred term
RNA Interference
Type
-
Topical Descriptor
Broader concept
Entry terms
- Gene Silencing, Post Transcriptional
- Gene Silencing, Post-Transcriptional
- Gene Silencing, Posttranscriptional
- Gene Silencings, Posttranscriptional
- Post Transcriptional Gene Silencing
- Post-Transcriptional Gene Silencing
- Posttranscriptional Gene Silencing
- Post-Transcriptional Gene Silencings
- RNAi
- RNA Silencing
- Silencing, Post-Transcriptional Gene
Scope note
- A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.
History note
- 2003
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D034622
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