Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > RNA-Binding Protein EWS
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Neoplasm Proteins > Oncogene Proteins > Proto-Oncogene Proteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > Heterogeneous-Nuclear Ribonucleoproteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > RNA Recognition Motif Proteins > Heterogeneous-Nuclear Ribonucleoproteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > Ribonucleoproteins > Heterogeneous-Nuclear Ribonucleoproteins > RNA-Binding Protein EWS
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > Ribonucleoproteins > Heterogeneous-Nuclear Ribonucleoproteins > RNA-Binding Protein EWS
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Calmodulin-Binding Proteins > RNA-Binding Protein EWS

Preferred term

RNA-Binding Protein EWS  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Ewing Sarcoma Breakpoint Region 1 Protein
  • Ewing Sarcoma Breakpointregion 1 Protein
  • EWS Protein
  • EWS Proto Oncogene Protein
  • EWS Proto-Oncogene Protein
  • EWSR1 Protein
  • EWS RNA Binding Protein 1
  • Protein, EWSR1
  • Proto-Oncogene Protein, EWS

Scope note

  • A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.

History note

  • 2003; for EWS PROTEIN use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS 1995-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D034802

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/3/02, last modified 4/5/23