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Macromolecular Substances > Multiprotein Complexes > Shelterin Complex > Telomeric Repeat Binding Protein 1

Preferred term

Telomeric Repeat Binding Protein 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • TERF1 Protein
  • TERF1 Proteins
  • TRF1 Protein
  • TRF1 Proteins
  • TTAGGG Repeat Binding Factor 1

Scope note

  • A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.

History note

  • 2003; for TRF1 PROTEIN use TELOMERE-BINDING PROTEINS (NM) 1997-2002;

In other languages

URI

http://www.yso.fi/onto/mesh/D035321

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