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Amino Acids, Peptides, and Proteins > Proteins > Iron-Regulatory Proteins > Iron Regulatory Protein 1
Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > Iron Regulatory Protein 1
Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > Iron Regulatory Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Iron-Binding Proteins > Nonheme Iron Proteins > Iron-Sulfur Proteins > Iron Regulatory Protein 1
... > Amino Acids, Peptides, and Proteins > Proteins > Metalloproteins > Iron-Binding Proteins > Nonheme Iron Proteins > Iron-Sulfur Proteins > Iron Regulatory Protein 1
... > Enzymes and Coenzymes > Enzymes > Lyases > Carbon-Oxygen Lyases > Hydro-Lyases > Aconitate Hydratase > Iron Regulatory Protein 1

Preferred term

Iron Regulatory Protein 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • ACO1 Protein
  • Aconitase 1, Soluble
  • Ferritin Repressor Protein
  • IRE BP1
  • IRE-BP1
  • IRP 1 Protein
  • IRP-1 Protein
  • IRP1 Protein
  • Repressor Protein, Ferritin
  • Soluble Aconitase 1

Scope note

  • A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.

History note

  • 2003; for FERRITIN REPRESSOR PROTEIN use IRON-REGULATORY PROTEINS (NM) 1991-2002, for IRE-BP1, IRON REGULATORY PROTEIN 1, IRP-1 PROTEIN & IRP1 PROTEIN use IRON-REGULATORY PROTEINS (NM) 1995-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D035941

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RDF/XML TURTLE JSON-LD Created 7/2/02, last modified 7/5/06