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Concept information

Preferred term

Iron Regulatory Protein 2  

Type

  • Topical Descriptor

Entry terms

  • IREB2 Protein
  • IRE-BP2
  • Iron-Responsive-Element Binding Protein 2
  • IRP2 Protein
  • IRP 2 RNA binding protein
  • IRP-2 RNA-binding protein
  • RNA-binding protein, IRP-2

Scope note

  • A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its rate of degradation is increased in the presence of IRON.

History note

  • 2003; for IRON REGULATORY PROTEIN 2, IRE-BP2 & IRP-2 RNA-BINDING PROTEIN use IRON-REGULATORY PROTEINS (NM) 1995-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D035942

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