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Concept information

Preferred term

Receptor, EphA1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • EPHA1 Protein
  • EphA1 Receptor
  • EPHA1 Receptor Tyrosine Kinase
  • Eph Receptor

Scope note

  • The founding member of the EPH FAMILY RECEPTORS. It was first cloned from an erythropoietin-producing human hepatocellular carcinoma cell line and is highly conserved among many mammalian species. Overproduction of the EphA1 receptor is associated with tumors and tumor cells of epithelial origin. It is also expressed at high levels in LIVER; LUNG; and KIDNEY; which is in contrast to many other members of the Eph receptor that are found primarily in tissues of the nervous system.

History note

  • 2003; use RECEPTOR, EPHA1 (NM) 1999-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D036082

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