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Concept information

Preferred term

Thyroid Hormone Receptors beta  

Type

  • Topical Descriptor

Entry terms

  • c erbA beta
  • c-erbA beta
  • ERBA2 Gene Products
  • Gene Products, ERBA2
  • Gene Products, NR1A2
  • Gene Products, THRB
  • NR1A2 Gene Products
  • Receptors beta, Thyroid Hormone
  • THRB Gene Products
  • Thyroid Hormone Receptor beta
  • TR beta

Scope note

  • High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.

History note

  • 2003; use RECEPTORS, THYROID HORMONE 1994-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D037042

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