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Amino Acids, Peptides, and Proteins > Proteins > Lectins > Calreticulin
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Intracellular Calcium-Sensing Proteins > Calreticulin
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Intracellular Calcium-Sensing Proteins > Calreticulin
... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Calcium-Binding Proteins > Intracellular Calcium-Sensing Proteins > Calreticulin

Preferred term

Calreticulin  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 55 kDa High Affinity Calcium Binding Protein
  • 55-kDa High-Affinity Calcium Binding Protein
  • CAB-63
  • Calcium Binding Protein 3
  • Calcium-Binding Protein-3
  • Calregulin
  • CBP3 (Liver)
  • cC1qR Protein
  • ERp60
  • HACBP

Scope note

  • A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.

History note

  • 2003; use CALRETICULIN (NM) 1990-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D037282

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