Concept information
Preferred term
Pulmonary Surfactant-Associated Protein A
Type
-
Topical Descriptor
Broader concept
Entry terms
- SP A Protein
- SP-A Protein
- Surfactant Protein A
Scope note
- An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
History note
- 2003; for SURFACTANT PROTEIN A & SP-A PROTEIN use PULMONARY SURFACTANT-ASSOCIATED PROTEINS (NM) 1991-2002
In other languages
URI
http://www.yso.fi/onto/mesh/D037662
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