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Concept information

Preferred term

alpha-Crystallins  

Type

  • Topical Descriptor

Entry terms

  • alpha Crystallin
  • alpha-Crystallin
  • Crystallins, alpha

Scope note

  • A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.

History note

  • 2003; for ALPHA-CRYSTALLIN use CRYSTALLINS 1982-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D038201

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