Concept information
Preferred term
alpha-Crystallins
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- alpha Crystallin
- alpha-Crystallin
- Crystallins, alpha
Scope note
- A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.
History note
- 2003; for ALPHA-CRYSTALLIN use CRYSTALLINS 1982-2002
In other languages
-
Finnish
-
alfakristalliini
-
Swedish
URI
http://www.yso.fi/onto/mesh/D038201
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