Concept information
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Molecular Sequence Data
Base Sequence
Regulatory Sequences, Nucleic Acid
Regulatory Sequences, Ribonucleic Acid
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Genetic Structures
Base Sequence
Regulatory Sequences, Nucleic Acid
Regulatory Sequences, Ribonucleic Acid
Preferred term
RNA 5' Terminal Oligopyrimidine Sequence
Type
-
Topical Descriptor
Broader concept
Entry terms
- 5' TOP Sequence
- 5' TOP Sequences
- RNA 5' Terminal Oligopyrimidine Regulatory Sequence
- Sequence, 5' TOP
- Sequences, 5' TOP
Scope note
- A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.
History note
- 2003
In other languages
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Finnish
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RNA 5' terminaalinen oligopyrimidiinijakso
URI
http://www.yso.fi/onto/mesh/D038641
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