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Concept information

Preferred term

RNA 5' Terminal Oligopyrimidine Sequence  

Type

  • Topical Descriptor

Entry terms

  • 5' TOP Sequence
  • 5' TOP Sequences
  • RNA 5' Terminal Oligopyrimidine Regulatory Sequence
  • Sequence, 5' TOP
  • Sequences, 5' TOP

Scope note

  • A regulatory sequence found in the 5' terminal regions of a variety of RNA species. The sequence starts with a CYTIDINE, which is followed by a stretch of 5 to 15 PYRIMIDINE NUCLEOTIDES. Messenger RNA that contains the 5' Terminal Oligo Pyrimidine tract is often referred to as 5' TOP mRNA. The sequence acts as a translational regulator and has been found in mRNAs for PEPTIDE ELONGATION FACTORS and RIBOSOMAL PROTEINS.

History note

  • 2003

In other languages

URI

http://www.yso.fi/onto/mesh/D038641

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