Concept information
Preferred term
Follistatin
Type
-
Topical Descriptor
Broader concept
Entry terms
- Activin Binding Protein
- Activin-Binding Protein
Scope note
- A broadly distributed protein that binds directly to ACTIVINS. It functions as an activin antagonist, inhibits FOLLICLE STIMULATING HORMONE secretion, regulates CELL DIFFERENTIATION, and plays an important role in embryogenesis. Follistatin is a single glycosylated polypeptide chain of approximately 37-kDa and is not a member of the inhibin family (INHIBINS). Follistatin also binds and neutralizes many members of the TRANSFORMING GROWTH FACTOR BETA family.
History note
- 2003; use FOLLISTATIN (NM) 1988-2002
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D038681
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