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Concept information

Preferred term

Ribosomal Protein S6 Kinases, 70-kDa  

Type

  • Topical Descriptor

Entry terms

  • p70s6k
  • p70 S6 Kinase
  • S6 Kinase, p70

Scope note

  • A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.

History note

  • 2005(2003); for P70 S6 KINASE & P70S6K use RIBOSOMAL PROTEIN S6 KINASES 1998-2002

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URI

http://www.yso.fi/onto/mesh/D038762

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