Concept information
...
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Ribosomal Protein S6 Kinases
Preferred term
Ribosomal Protein S6 Kinases, 70-kDa
Type
-
Topical Descriptor
Broader concept
Entry terms
- p70s6k
- p70 S6 Kinase
- S6 Kinase, p70
Scope note
- A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.
History note
- 2005(2003); for P70 S6 KINASE & P70S6K use RIBOSOMAL PROTEIN S6 KINASES 1998-2002
In other languages
-
Finnish
-
ribosomaalinen proteiini S6 -kinaasi, 70kDa
-
Swedish
URI
http://www.yso.fi/onto/mesh/D038762
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}