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... > Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > RNA-Binding Proteins > RNA Splicing Factors > Polypyrimidine Tract-Binding Protein
... > Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > RNA-Binding Proteins > RNA Splicing Factors > Polypyrimidine Tract-Binding Protein

Preferred term

Polypyrimidine Tract-Binding Protein  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • p57 Cytoplasmic RNA Binding Protein
  • p57 Cytoplasmic RNA-Binding Protein
  • pPTB
  • PTB Protein
  • PTB Splicing Factor
  • Splicing Factor, PTB

Scope note

  • A RNA-binding protein that binds to polypyriminidine rich regions in the INTRONS of messenger RNAs. Polypyrimidine tract-binding protein may be involved in regulating the ALTERNATIVE SPLICING of mRNAs since its presence on an intronic RNA region that is upstream of an EXON inhibits the splicing of the exon into the final mRNA product.

History note

  • 2003; use POLYPYRIMIDINE TRACT-BINDING PROTEIN (NM) 1991-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D038941

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