Concept information
Preferred term
Integrin alpha4beta1
Type
-
Topical Descriptor
Entry terms
- alpha4beta1 Integrin
- alpha4beta1, Integrin Heterodimer
- Antigen-4, Very Late
- CD49d-CD29
- Heterodimer alpha4beta1, Integrin
- Integrin alpha(4)beta(1)
- Integrin, alpha4beta1
- Integrin Heterodimer alpha4beta1
- Late Antigen-4, Very
- Very Late Activation Antigen 4
- Very Late Activation Antigen-4
- Very Late Antigen 4
- Very Late Antigen-4
- VLA-4
Scope note
- Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.
History note
- 2003 (1991)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D039041
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