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Concept information

Preferred term

Integrin alpha4beta1  

Type

  • Topical Descriptor

Entry terms

  • alpha4beta1 Integrin
  • alpha4beta1, Integrin Heterodimer
  • Antigen-4, Very Late
  • CD49d-CD29
  • Heterodimer alpha4beta1, Integrin
  • Integrin alpha(4)beta(1)
  • Integrin, alpha4beta1
  • Integrin Heterodimer alpha4beta1
  • Late Antigen-4, Very
  • Very Late Activation Antigen 4
  • Very Late Activation Antigen-4
  • Very Late Antigen 4
  • Very Late Antigen-4
  • VLA-4

Scope note

  • Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

History note

  • 2003 (1991)

In other languages

URI

http://www.yso.fi/onto/mesh/D039041

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