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Concept information

Preferred term

Integrin alpha3beta1  

Type

  • Topical Descriptor

Entry terms

  • alpha3beta1 Epiligrin Receptor
  • alpha3beta1 Integrin
  • CD49c-CD29
  • Epiligrin Receptor
  • Epiligrin Receptor, alpha3beta1
  • Galactoprotein b3
  • Gap b3
  • Integrin alpha(3)beta(1)
  • Integrin, alpha3beta1
  • Laminin-5 Receptor (alpha3beta1 integrin)
  • Receptor, alpha3beta1 Epiligrin
  • Receptor, Epiligrin
  • VLA-3

Scope note

  • Cell surface receptor for LAMININ, epiligrin, FIBRONECTINS, entactin, and COLLAGEN. Integrin alpha3beta1 is the major integrin present in EPITHELIAL CELLS, where it plays a role in the assembly of BASEMENT MEMBRANE as well as in cell migration, and may regulate the functions of other integrins. Two alternatively spliced isoforms of the alpha subunit (INTEGRIN ALPHA3), are differentially expressed in different cell types.

History note

  • 2003; use INTEGRIN ALPHA3BETA1 (NM) 1992-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D039201

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