Concept information
Preferred term
Cleavage And Polyadenylation Specificity Factor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cleavage Polyadenylation Specificity Factor
- Cleavage-Polyadenylation Specificity Factor
- CPSF Protein
Scope note
- An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
History note
- 2003; for CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR use MRNA CLEAVAGE AND POLYADENYLATION FACTORS (NM) 1992-2002
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D039223
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