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... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Neurotransmitter Agents > Histamine Agents > Histamine Antagonists > Histamine H1 Antagonists > Histamine H1 Antagonists, Non-Sedating
... > Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Neurotransmitter Agents > Histamine Agents > Histamine Antagonists > Histamine H1 Antagonists > Histamine H1 Antagonists, Non-Sedating

Preferred term

Histamine H1 Antagonists, Non-Sedating  

Type

  • Topical Descriptor

Broader concept

Related concepts

Entry terms

  • Antihistamine, Second Generation
  • Antihistamines, Second Generation
  • Generation Antihistamine, Second
  • H1 Antihistamines, Non Sedating
  • H1 Antihistamines, Non-Sedating
  • Non-Sedating H1 Antihistamines
  • Second Generation Antihistamine
  • Second Generation Antihistamines
  • Second Generation H1 Antagonist
  • Second Generation H1 Antagonists

Scope note

  • A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.

History note

  • 2003

In other languages

URI

http://www.yso.fi/onto/mesh/D039563

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