Concept information
Preferred term
Eukaryotic Initiation Factor-3
Type
-
Topical Descriptor
Broader concept
Entry terms
- EIF-3
- EIF3
- Eukaryotic Peptide Initiation Factor 3
- Eukaryotic Peptide Initiation Factor-3
- Peptide Initiation Factor EIF 3
- Peptide Initiation Factor EIF-3
Scope note
- A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit.
History note
- 2003; use EUKARYOTIC INITIATION FACTOR-3 (NM) 1990-2002
URI
http://www.yso.fi/onto/mesh/D039621
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