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Concept information

Preferred term

Eukaryotic Initiation Factor-3  

Type

  • Topical Descriptor

Entry terms

  • EIF-3
  • EIF3
  • Eukaryotic Peptide Initiation Factor 3
  • Eukaryotic Peptide Initiation Factor-3
  • Peptide Initiation Factor EIF 3
  • Peptide Initiation Factor EIF-3

Scope note

  • A multisubunit eukaryotic initiation factor that contains at least 8 distinct polypeptides. It plays a role in recycling of ribosomal subunits to the site of transcription initiation by promoting the dissociation of non-translating ribosomal subunits. It also is involved in promoting the binding of a ternary complex of EUKARYOTIC INITIATION FACTOR-2; GTP; and INITIATOR TRNA to the 40S ribosomal subunit.

History note

  • 2003; use EUKARYOTIC INITIATION FACTOR-3 (NM) 1990-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D039621

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