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Concept information

Preferred term

Integrin beta Chains  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • beta Integrins
  • Integrin beta Subunits
  • Integrins, beta

Scope note

  • Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.

History note

  • 2003

In other languages

URI

http://www.yso.fi/onto/mesh/D039641

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