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Concept information

Preferred term

Leukocyte L1 Antigen Complex  

Type

  • Topical Descriptor

Narrower concepts

Entry terms

  • 27E10 Antigen
  • Antigen, 27E10
  • Antigen, L1
  • Antigen L1, Myelomonocytic
  • Calcium Binding Myeloid Protein P8,14
  • Calcium-Binding Myeloid Protein P8,14
  • Calgranulin
  • Calprotectin
  • L1 Antigen
  • L1 Protein, Leukocyte
  • Leukocyte L1 Protein
  • Migratory Inhibitory Factor Related Protein MRP
  • Migratory Inhibitory Factor-Related Protein MRP
  • Myelomonocytic Antigen L1

Scope note

  • A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.

History note

  • 2003; use LEUKOCYTE L1 ANTIGEN COMPLEX (NM) 1984-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D039841

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