Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Neuropilins > Neuropilin-2

Preferred term

Neuropilin-2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Npn 2 Protein
  • Npn-2 Protein
  • NRP2 Protein

Scope note

  • Transmembrane receptor for CLASS 3 SEMAPHORINS and several vascular endothelial growth factor isoforms. Neuropilin-2 functions either as a homodimer or as a heterodimer with NEUROPILIN-1. The binding affinity of neuropilin-2 varies for different class 3 semaphorin isoforms and is dependent on the composition of the dimer. The protein also forms receptor complexes with plexins and with VEGF RECEPTORS, which alters the binding characteristics of the receptor.

History note

  • 2003; for NPN-2 PROTEIN use NEUROPILIN-1 1998-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D039943

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/3/02, last modified 5/31/16