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Concept information

Preferred term

Semaphorin-3A  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Collapsin
  • Collapsin 1
  • Collapsin-1
  • Collapsing Factor
  • Sema3A
  • Semaphorin 3A
  • Semaphorin D
  • Sem D

Scope note

  • The prototypical and most well-studied member of the semaphorin family. Semaphorin-3A is an axon-repulsive guidance cue for migrating neurons in the developing nervous system. It has so far been found only in vertebrates, and binds to NEUROPILIN-1/plexin complex receptors on growth cones. Like other class 3 semaphorins, it is a secreted protein.

History note

  • 2003; use SEMAPHORIN 3A (NM) 1994-2002

In other languages

URI

http://www.yso.fi/onto/mesh/D040121

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