Concept information
...
Membrane Proteins
Receptors, Cell Surface
Receptor Protein-Tyrosine Kinases
Receptors, Vascular Endothelial Growth Factor
...
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Receptors, Vascular Endothelial Growth Factor
...
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Receptors, Vascular Endothelial Growth Factor
Preferred term
Vascular Endothelial Growth Factor Receptor-1
Type
-
Topical Descriptor
Broader concept
Entry terms
- FLT1 Receptor Tyrosine Kinase
- FLT1 RTK
- FLT VEGF Receptor
- fms-Like Tyrosine Kinase
- Proto Oncogene Protein flt
- Proto-Oncogene Protein flt
- Receptor, FLT VEGF
- Tyrosine Kinase, fms-Like
- VEGFR-1
- VEGF Receptor, FLT
- VEGF Receptor flt 1 Protein
- VEGF Receptor flt-1 Protein
Scope note
- A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction.
History note
- 2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D040281
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}