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Biological Factors > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Angiopoietins > Angiopoietin-2
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Angiopoietins > Angiopoietin-2
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Angiogenic Proteins > Angiopoietins > Angiopoietin-2

Preferred term

Angiopoietin-2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Angiopoietin 2

Scope note

  • An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.

History note

  • 2004; use ANGIOPOIETIN-2 (NM) 1997-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D042702

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RDF/XML TURTLE JSON-LD Created 7/9/03, last modified 7/5/06