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... > Chemical Actions and Uses > Pharmacologic Actions > Physiological Effects of Drugs > Hormones, Hormone Substitutes, and Hormone Antagonists > Hormones > Gonadal Hormones > Gonadal Steroid Hormones > Estradiol Congeners > Estrogenic Steroids, Alkylated

Preferred term

Estrogenic Steroids, Alkylated  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Alkylated Estrogenic Steroids
  • Alkyl Estrogenic Steroids

Scope note

  • Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.

History note

  • 2004

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URI

http://www.yso.fi/onto/mesh/D042782

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