Concept information
...
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Receptors, TIE
Preferred term
Receptor, TIE-2
Type
-
Topical Descriptor
Broader concept
Entry terms
- Angiopoietin Receptor Tie 2
- Angiopoietin Receptor Tie-2
- Receptor, Tek
- Receptor, Tie2
- Receptor Tie-2, Angiopoietin
- Tek Receptor
- Tie-2, Angiopoietin Receptor
- Tie2 Receptor
- TIE 2 Receptor Tyrosine Kinase
- TIE-2 Receptor Tyrosine Kinase
- TIE-2-RTK
- TIE2 Tyrosine Kinase
- Tyrosine Kinase, TIE2
Note
- see SCR for organism-specific terms
Scope note
- A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
History note
- 2004; use RECEPTOR TIE-2 (NM) 1993-2003
In other languages
-
Finnish
-
TIE-2-tyrosiinikinaasireseptori
-
Swedish
-
Receptor, TIE-2
URI
http://www.yso.fi/onto/mesh/D042787
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}