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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Carboxylic Ester Hydrolases > Phospholipases > Phospholipases A > Phospholipases A2 > 1-Alkyl-2-acetylglycerophosphocholine Esterase
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Diester Hydrolases > Phospholipases > Phospholipases A > Phospholipases A2 > 1-Alkyl-2-acetylglycerophosphocholine Esterase

Preferred term

1-Alkyl-2-acetylglycerophosphocholine Esterase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 2-Acetylhydrolase, PAF
  • Acetylhydrolase II, PAF
  • Acetylhydrolase, PAF
  • Factor Hydrolase, Platelet-Activating
  • Hydrolase, Platelet-Activating Factor
  • Lipoprotein Associated Phospholipase A2
  • Lipoprotein-Associated Phospholipase A(2)
  • Lipoprotein-Associated Phospholipase A2
  • Lp PLA2
  • Lp-PLA(2)
  • Lp-PLA2
  • PAF 2 Acetylhydrolase
  • PAF 2-Acetylhydrolase
  • PAF 2 Acylhydrolase
  • PAF 2-Acylhydrolase
  • PAF Acetylhydrolase
  • PAF Acetylhydrolase II
  • Phospholipase A2, Lipoprotein-Associated
  • Platelet Activating Factor Hydrolase
  • Platelet-Activating Factor Hydrolase

Note

  • /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS

Scope note

  • A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.

History note

  • 2004(1983)

In other languages

URI

http://www.yso.fi/onto/mesh/D043203

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