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Concept information

Preferred term

DNA Sequence, Unstable  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Unstable DNA Sequence
  • Unstable DNA Sequences

Scope note

  • A region of DNA that is highly polymorphic and is prone to strand breaks, rearrangements or other MUTATIONS because of the nature of its sequence. These regions often harbor palindromic, or repetitive sequences (REPETITIVE SEQUENCES, NUCLEIC ACID). Variability in stability of the DNA sequence is seen at CHROMOSOME FRAGILE SITES.

History note

  • 2004 (1998); use TRINUCLEOTIDE REPEAT EXPANSION 1998-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D043243

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