Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Enzymes and Coenzymes > Enzymes > DNA Repair Enzymes > DNA-(Apurinic or Apyrimidinic Site) Lyase
Enzymes and Coenzymes > Enzymes > Lyases > Carbon-Oxygen Lyases > DNA-(Apurinic or Apyrimidinic Site) Lyase

Preferred term

DNA-(Apurinic or Apyrimidinic Site) Lyase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • AP Endonuclease
  • AP Lyase
  • Apurine Apyrimidine Endonuclease
  • Apurine-Apyrimidine Endonuclease
  • Apurinic DNA Endonuclease
  • Apurinic Endonuclease
  • DNA Endonuclease, Apurinic
  • DNA Lyase (Apurinic or Apyrimidinic)
  • Endodeoxyribonuclease (Apurinic or Apyrimidinic)
  • Endonuclease, AP
  • Endonuclease, Apurine-Apyrimidine
  • Endonuclease, Apurinic
  • Endonuclease, Apurinic DNA

Scope note

  • A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2.

History note

  • 2004; use DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE (NM) 1980-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D043603

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/9/03, last modified 7/9/13