Concept information
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Receptors, Cell Surface
Receptors, G-Protein-Coupled
Receptors, Serotonin
Receptors, Serotonin, 5-HT1
...
Receptors, Cell Surface
Receptors, Biogenic Amine
Receptors, Serotonin
Receptors, Serotonin, 5-HT1
Preferred term
Receptor, Serotonin, 5-HT1D
Type
-
Topical Descriptor
Broader concept
Entry terms
- 5 HT1D Receptor
- 5-HT(1D) Receptor
- 5-HT1D Receptor
- 5 Hydroxytryptamine1D Receptor
- 5-Hydroxytryptamine1D Receptor
- Receptor, 5-HT1D
- Receptor, 5-Hydroxytryptamine1D
- Receptor, Serotonin 1D
- Receptors, Serotonin 1D
- Serotonin 1D Receptor
- Serotonin 1D Receptors
Scope note
- A serotonin receptor subtype that is localized to the CAUDATE NUCLEUS; PUTAMEN; the NUCLEUS ACCUMBENS; the HIPPOCAMPUS, and the RAPHE NUCLEI. It plays a role as a terminal autoreceptor that regulates the rate of SEROTONIN release from nerve endings. This serotonin receptor subtype is closely related to and has similar drug binding properties as the 5-HT1B RECEPTOR, but is expressed at low levels. It is particularly sensitive to the agonist SUMATRIPTAN and may be involved in mediating the drug's antimigrane effect.
History note
- 2004; use RECEPTOR, SEROTONIN, 5-HT1D (NM) 1996-2003
In other languages
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Finnish
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serotoniini 1D -reseptori
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Swedish
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5-HT(1Dalpha) receptor
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5-HT1D receptor
URI
http://www.yso.fi/onto/mesh/D044346
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