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Concept information

Preferred term

beta-Mannosidase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • beta D Mannosidase
  • beta-D-Mannosidase
  • beta Mannanase
  • beta-Mannanase
  • manA protein (beta-Mannosidase)

Note

  • /defic: consider also BETA-MANNOSIDOSIS

Scope note

  • An enzyme that catalyzes the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides. The enzyme plays a role in the lysosomal degradation of the N-glycosylprotein glycans. Defects in the lysosomal form of the enzyme in humans result in a buildup of mannoside intermediate metabolites and the disease BETA-MANNOSIDOSIS.

History note

  • 2004; use BETA-MANNOSIDASE (NM) 1980-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D044902

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