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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Proprotein Convertase 1
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Proprotein Convertase 1
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Proprotein Convertases > Proprotein Convertase 1

Preferred term

Proprotein Convertase 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Convertase PC1, Neuroendocrine
  • Convertase, PC1 Prohormone
  • Convertase, PC3 Prohormone
  • Convertase SPC3, Proprotein
  • Endoprotease, PC1
  • Endoprotease, PC3
  • Neuroendocrine Convertase PC1
  • PC1 Endoprotease
  • PC1 Prohormone Convertase
  • PC3 Endoprotease
  • PC3 Prohormone Convertase
  • Prohormone Convertase 1
  • Prohormone Convertase 3
  • Prohormone Convertase, PC1
  • Prohormone Convertase, PC3
  • Proinsulin Convertase 1
  • Proprotein Convertase SPC3

Scope note

  • A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.

History note

  • 2004; for PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE, PROHORMONE CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 1991-2003; for PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE use PROPROTEIN CONVERTASE (NM) 1993-2003; for PROPROTEIN CONVERTASE SPC3 use PROPROTEIN CONVERTASE (NM) 2001-2003; for PROINSULIN CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 2002-2003

In other languages

URI

http://www.yso.fi/onto/mesh/D045664

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