Concept information
Preferred term
Proteasome Endopeptidase Complex
Type
-
Topical Descriptor
Broader concept
Entry terms
- 20S Proteasome
- Complex, Multicatalytic Endopeptidase
- Endopeptidase Complex, Multicatalytic
- Macropain
- Macroxyproteinase
- Multicatalytic Endopeptidase Complex
- Multicatalytic Proteinase
- Prosome
- Proteasome
- Proteasome, 20S
- Proteinase, Multicatalytic
Scope note
- A large multisubunit complex that plays an important role in the degradation of most of the cytosolic and nuclear proteins in eukaryotic cells. It contains a 700-kDa catalytic sub-complex and two 700-kDa regulatory sub-complexes. The complex digests ubiquitinated proteins and protein activated via ornithine decarboxylase antizyme.
History note
- 2005; use PROTEASOME ENDOPEPTIDASE COMPLEX (NM) 1986-2004
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D046988
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