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Concept information

Preferred term

Receptors, Tumor Necrosis Factor, Type I  

Type

  • Topical Descriptor

Entry terms

  • 120a Antigen, CD
  • Antigen, CD 120a
  • Antigen, CD120a
  • Antigens, CD120a
  • CD 120a Antigen
  • CD120a Antigen
  • CD120a Antigens
  • Receptors, Tumor Necrosis Factor, Member 1A
  • Receptor, TNFRSF1A
  • TNFR1
  • TNFR-I
  • TNFR p60
  • TNFRSF1A Receptor
  • TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A)
  • Tumor Necrosis Factor Receptor 1A
  • Tumor Necrosis Factor Receptor Superfamily, Member 1A
  • Tumor Necrosis Factor Receptor Type 1
  • Tumor Necrosis Factor Receptor Type I

Scope note

  • A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.

History note

  • 2005(1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D047888

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