Concept information
Preferred term
Receptors, Tumor Necrosis Factor, Type I
Type
-
Topical Descriptor
Broader concept
Entry terms
- 120a Antigen, CD
- Antigen, CD 120a
- Antigen, CD120a
- Antigens, CD120a
- CD 120a Antigen
- CD120a Antigen
- CD120a Antigens
- Receptors, Tumor Necrosis Factor, Member 1A
- Receptor, TNFRSF1A
- TNFR1
- TNFR-I
- TNFR p60
- TNFRSF1A Receptor
- TNFRSF1A (Tumor Necrosis Factor Receptor Superfamily, Member 1A)
- Tumor Necrosis Factor Receptor 1A
- Tumor Necrosis Factor Receptor Superfamily, Member 1A
- Tumor Necrosis Factor Receptor Type 1
- Tumor Necrosis Factor Receptor Type I
Scope note
- A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
History note
- 2005(1994)
In other languages
-
Finnish
-
CD120a-antigeeni
-
CD120a-antigeenit
-
tyypin I TNF-reseptori
-
Swedish
URI
http://www.yso.fi/onto/mesh/D047888
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