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Amino Acids, Peptides, and Proteins > Proteins > Carrier Proteins > Adaptor Proteins, Signal Transducing > 14-3-3 Proteins
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > 14-3-3 Proteins
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Adaptor Proteins, Signal Transducing > 14-3-3 Proteins

Preferred term

14-3-3 Proteins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • 14 3 3 Protein
  • 14-3-3 Protein
  • 14-3-3 Protein, Brain
  • Brain 14 3 3 Protein
  • Brain 14-3-3 Protein
  • Protein 14-3-3

Scope note

  • A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins.

History note

  • 2005(1981)

In other languages

URI

http://www.yso.fi/onto/mesh/D048948

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