Concept information
Preferred term
Transient Receptor Potential Channels
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Cation Channels, TRP
- Cation Channel, TRP
- Channels, TRP Cation
- Channel, TRP Cation
- Membrane Proteins, TRP
- Proteins, TRP Membrane
- Transient Receptor Potential Cation Channel
- Transient Receptor Potential Cation Channels
- Transient Receptor Potential Channel
- TRP Cation Channel
- TRP Cation Channels
- TRP Membrane Proteins
Note
- note entry terms: TRP refers to transient receptor potential not TRYPTOPHAN
Scope note
- A broad group of eukaryotic six-transmembrane cation channels that are classified by sequence homology because their functional involvement with SENSATION is varied. They have only weak voltage sensitivity and ion selectivity. They are named after a DROSOPHILA mutant that displayed transient receptor potentials in response to light. A 25-amino-acid motif containing a TRP box (EWKFAR) just C-terminal to S6 is found in TRPC, TRPV and TRPM subgroups. ANKYRIN REPEATS are found in TRPC, TRPV & TRPN subgroups. Some are functionally associated with TYROSINE KINASE or TYPE C PHOSPHOLIPASES.
History note
- 2006
In other languages
-
Finnish
URI
http://www.yso.fi/onto/mesh/D050051
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