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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxygenases > Mixed Function Oxygenases > Squalene Monooxygenase

Preferred term

Squalene Monooxygenase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Epoxidase, Squalene
  • Squalene Epoxidase
  • Squalene Monooxygenase (2,3-Epoxidizing)

Scope note

  • The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.

History note

  • 2006(1980); use ETHERS, CYCLIC 1970-1979

In other languages

URI

http://www.yso.fi/onto/mesh/D050603

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