Concept information
Preferred term
Mannose-Binding Protein-Associated Serine Proteases
Type
-
Topical Descriptor
Broader concept
Entry terms
- Mannan Binding Lectin Serine Proteases
- Mannan-Binding Lectin Serine Proteases
- Mannose Binding Protein Associated Serine Protease
- Mannose-Binding Protein-Associated Serine Protease
- MASP
- MASP Proteases
- MASPs
- MBL Associated Serine Proteases
- MBL-Associated Serine Proteases
- MBP Associated Serine Protease
- MBP-Associated Serine Protease
- Proteases, MASP
- Serine Protease, MBP-Associated
- Serine Proteases, MBL-Associated
Note
- see SCR for organism-specific terms
Scope note
- Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
History note
- 2006 (1994)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D050606
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