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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxidoreductases Acting on Aldehyde or Oxo Group Donors > Aldehyde Oxidoreductases > Succinate-Semialdehyde Dehydrogenase

Preferred term

Succinate-Semialdehyde Dehydrogenase  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Dehydrogenase, Succinate Semialdehyde
  • Dehydrogenase, Succinic Semialdehyde
  • NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase
  • Semialdehyde Dehydrogenase, Succinate
  • Semialdehyde Dehydrogenase, Succinic
  • Succinate Semialdehyde Dehydrogenase
  • Succinic Semialdehyde Dehydrogenase

Scope note

  • An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).

History note

  • 2006(1980); use ALDEHYDE OXIDREDUCTASES 1977-1979

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URI

http://www.yso.fi/onto/mesh/D050644

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