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... > Enzymes and Coenzymes > Enzymes > Oxidoreductases > Oxidoreductases Acting on Aldehyde or Oxo Group Donors > Aldehyde Oxidoreductases > Methylmalonate-Semialdehyde Dehydrogenase (Acylating)

Preferred term

Methylmalonate-Semialdehyde Dehydrogenase (Acylating)  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Dehydrogenase, MMSA
  • Methylmalonic-Semialdehyde Dehydrogenase (Acylating)
  • MMSA Dehydrogenase
  • MMSDH

Scope note

  • An enzyme that plays a role in the VALINE; LEUCINE; and ISOLEUCINE catabolic pathways by catalyzing the oxidation of 2-methyl-3-oxopropanate to propanoyl-CoA using NAD+ as a coenzyme. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated BETA-ALANINE and 3-hydropropionic acid.

History note

  • 2006(1987)

In other languages

URI

http://www.yso.fi/onto/mesh/D050646

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