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Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Core Binding Factors > Core Binding Factor alpha Subunits

Preferred term

Core Binding Factor alpha Subunits  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Acute Myeloid Leukemia Proteins
  • Core Binding Factor alpha Proteins
  • PEBP2A Transcription Factors
  • Polyomavirus Enhancer A Binding Protein 2
  • Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
  • Runt Domain Factor
  • Runx Proteins
  • Transcription Factors, PEBP2A

Scope note

  • A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.

History note

  • 2006(1987)

In other languages

URI

http://www.yso.fi/onto/mesh/D050657

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