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Concept information

Preferred term

Core Binding Factor Alpha 1 Subunit  

Type

  • Topical Descriptor

Entry terms

  • Acute Myeloid Leukemia 3 Protein
  • AML3 Transcription Factor
  • CBFA 1 Protein
  • CBFA-1 Protein
  • CBFA1 Protein
  • CBFalpha1 Protein
  • CBFalpha Runt Domain Transcription Factor 1
  • Osf2 Transcription Factor
  • PEBP2alphaA Protein
  • Runx2 Protein
  • SEF1 Protein
  • SL3 3 Enhancer Factor 1
  • SL3-3 Enhancer Factor 1

Note

  • see SCR for organism-specific terms

Scope note

  • A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.

History note

  • 2006(1997)

In other languages

URI

http://www.yso.fi/onto/mesh/D050659

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