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... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Core Binding Factors > Core Binding Factor alpha Subunits > Core Binding Factor Alpha 2 Subunit

Preferred term

Core Binding Factor Alpha 2 Subunit  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Acute Myeloid Leukemia 1 Protein
  • Core Binding Factor Alpha 2 Protein
  • Core-Binding Factor Alpha 2 Protein
  • Pebp2a2 Protein
  • Runt Related Transcription Factor 1
  • Runt-Related Transcription Factor 1
  • Runx1 Protein

Scope note

  • A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.

History note

  • 2006(1993)

In other languages

URI

http://www.yso.fi/onto/mesh/D050676

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