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Concept information

Preferred term

E2F6 Transcription Factor  

Type

  • Topical Descriptor

Entry terms

  • E2F-6, Transcription Factor
  • E2F Transcription Factor 6 Protein
  • Transcription Factor E2F 6
  • Transcription Factor E2F-6

Note

  • see SCR for organism-specific terms

Scope note

  • An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.

History note

  • 2006(2004)

In other languages

URI

http://www.yso.fi/onto/mesh/D050701

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